Highlights and News

Trial offers hope for millions that jab could prevent rheumatoid arthritis - The Guardian
Trial offers hope for millions that jab could prevent rheumatoid arthritis  The Guardian
Factors associated with resolution of ultrasound subclinical synovitis in anti-CCP-positive individuals with musculoskeletal symptoms: a UK prospective cohort study - The Lancet
Factors associated with resolution of ultrasound subclinical synovitis in anti-CCP-positive individuals with musculoskeletal symptoms: a UK prospective cohort study  The Lancet
Psoriatic Arthritis in Ankle: Causes, Symptoms, and Treatment - Health Central
Psoriatic Arthritis in Ankle: Causes, Symptoms, and Treatment  Health Central
Rheumatoid arthritis - The Lancet
Rheumatoid arthritis  The Lancet
Rheumatoid Arthritis X-Ray: Diagnosis and Evaluation - Health Central
Rheumatoid Arthritis X-Ray: Diagnosis and Evaluation  Health Central
My job left me unable to dress myself. Then I got news no 21-year-old dreams of - Metro.co.uk
My job left me unable to dress myself. Then I got news no 21-year-old dreams of  Metro.co.uk
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients - Nature.com
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients  Nature.com
11 Signs Your Rheumatoid Arthritis May Be Getting Worse, and You Should See a Doctor - CreakyJoints
11 Signs Your Rheumatoid Arthritis May Be Getting Worse, and You Should See a Doctor  CreakyJoints
New arthritis drug could prevent disease in those at risk, trial finds - The Independent
New arthritis drug could prevent disease in those at risk, trial finds  The Independent
Early rheumatoid arthritis: Disease trajectories and pain - Medical Xpress
Early rheumatoid arthritis: Disease trajectories and pain  Medical Xpress
Osteoarthritis - World Health Organization (WHO)
Osteoarthritis  World Health Organization (WHO)
Arthritis drugs may reduce mortality and time in ICU for sickest COVID patients - Imperial College London
Arthritis drugs may reduce mortality and time in ICU for sickest COVID patients  Imperial College London
Rheumatoid arthritis: features, causes and diagnosis - The Pharmaceutical Journal
Rheumatoid arthritis: features, causes and diagnosis  The Pharmaceutical Journal
Global, regional, and national burden of rheumatoid arthritis, 1990-2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021 - The Lancet
Global, regional, and national burden of rheumatoid arthritis, 1990-2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021  The Lancet
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial - Nature.com
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial  Nature.com
Dr Ranj says Strictly will help Adam Thomas long-term health condition - Metro.co.uk
Dr Ranj says Strictly will help Adam Thomas long-term health condition  Metro.co.uk
The 4 Stages of Rheumatoid Arthritis Progression - CreakyJoints
The 4 Stages of Rheumatoid Arthritis Progression  CreakyJoints
Arthritis drug effective in treating sickest COVID-19 patients - Imperial College London
Arthritis drug effective in treating sickest COVID-19 patients  Imperial College London
Rheumatoid Arthritis Life Expectancy: What You Need to Know - Health Central
Rheumatoid Arthritis Life Expectancy: What You Need to Know  Health Central
Incidence and management of inflammatory arthritis in England before and during the COVID-19 pandemic: a population-level cohort study using OpenSAFELY - The Lancet
Incidence and management of inflammatory arthritis in England before and during the COVID-19 pandemic: a population-level cohort study using OpenSAFELY  The Lancet
Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY - The Lancet
Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY  The Lancet
Rheumatoid arthritis diagnosis and management: a clinical update - Nursing Times
Rheumatoid arthritis diagnosis and management: a clinical update  Nursing Times
Palliative care - World Health Organization (WHO)
Palliative care  World Health Organization (WHO)
Frailty may be reversible for some people with rheumatoid arthritis - Medical Xpress
Frailty may be reversible for some people with rheumatoid arthritis  Medical Xpress
How rheumatoid arthritis is treated, from medication to diet to exercise - inews
How rheumatoid arthritis is treated, from medication to diet to exercise  inews
Clinical trial shows rheumatoid arthritis drug could prevent disease - Medical Xpress
Clinical trial shows rheumatoid arthritis drug could prevent disease  Medical Xpress
Identification of SNPs associated with methotrexate treatment outcomes in patients with early rheumatoid arthritis - Frontiers
Identification of SNPs associated with methotrexate treatment outcomes in patients with early rheumatoid arthritis  Frontiers
Biomarker Test Could Predict Your RA Treatment Effectiveness - Health Central
Biomarker Test Could Predict Your RA Treatment Effectiveness  Health Central
New 'highly effective' treatment for rheumatoid arthritis on the way after breakthrough - inews
New 'highly effective' treatment for rheumatoid arthritis on the way after breakthrough  inews
Adalimumab is found to be a cost-effective treatment for early-stage Dupuytren's disease - Nuffield Department of Population Health
Adalimumab is found to be a cost-effective treatment for early-stage Dupuytren's disease  Nuffield Department of Population Health
Psoriatic Arthritis Prognosis and Outlook - Health Central
Psoriatic Arthritis Prognosis and Outlook  Health Central
Multimorbidity May Increase Risk, Duration of Hospitalization for Patients With RA - AJMC.com Managed Markets Network
Multimorbidity May Increase Risk, Duration of Hospitalization for Patients With RA  AJMC.com Managed Markets Network
9 Best Compression Gloves for Arthritis and Carpal Tunnel: Benefits, Features, and More - Healthline
9 Best Compression Gloves for Arthritis and Carpal Tunnel: Benefits, Features, and More  Healthline
Strictly's Adam Thomas sees 'more doctors' for arthritis - Metro.co.uk
Strictly's Adam Thomas sees 'more doctors' for arthritis  Metro.co.uk
8 Things You Need to Know About Menopause When You Have Rheumatoid Arthritis - Everyday Health
8 Things You Need to Know About Menopause When You Have Rheumatoid Arthritis  Everyday Health
ACR 2021: 11 New Things to Know About Rheumatoid Arthritis - CreakyJoints
ACR 2021: 11 New Things to Know About Rheumatoid Arthritis  CreakyJoints
Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol - Trials Journal
Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol  Trials Journal
Pill for arthritis could stop type 1 diabetes in its tracks - inews
Pill for arthritis could stop type 1 diabetes in its tracks  inews
Strictly's Adam Thomas 'may need medication for life' for chronic illness - Metro.co.uk
Strictly's Adam Thomas 'may need medication for life' for chronic illness  Metro.co.uk
A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients - Frontiers
A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients  Frontiers
Blocking the immune system in rheumatoid arthritis - The Pharmaceutical Journal
Blocking the immune system in rheumatoid arthritis  The Pharmaceutical Journal
What is arthritis? Treatments, relief and how to overcome the pain - The Mirror
What is arthritis? Treatments, relief and how to overcome the pain  The Mirror
29 Tips from Podiatrists for Managing Arthritis Pain in Your Feet - CreakyJoints
29 Tips from Podiatrists for Managing Arthritis Pain in Your Feet  CreakyJoints
Suspicious Symptoms Herald Early Rheumatoid Arthritis - MD Magazine
Suspicious Symptoms Herald Early Rheumatoid Arthritis  MD Magazine
Triple Treatment Effective in Early Rheumatoid Arthritis - Medscape
Triple Treatment Effective in Early Rheumatoid Arthritis  Medscape
UK waiting times for RA and PsA patients: an interview with Dr Marwan Bukhari, Consultant Rheumatologist at the University Hospitals of Morecambe Bay NHS Foundation Trust - News-Medical.Net
UK waiting times for RA and PsA patients: an interview with Dr Marwan Bukhari, Consultant Rheumatologist at the University Hospitals of Morecambe Bay NHS Foundation Trust  News-Medical.Net
9 Diseases That Can Mimic Fibromyalgia (and Delay Your Diagnosis) - CreakyJoints
9 Diseases That Can Mimic Fibromyalgia (and Delay Your Diagnosis)  CreakyJoints
Women who take HRT to help them through the menopause are almost 50% more likely to get arthritis, finds study - Daily Mail
Women who take HRT to help them through the menopause are almost 50% more likely to get arthritis, finds study  Daily Mail
Rheumatoid arthritis: management - The Pharmaceutical Journal
Rheumatoid arthritis: management  The Pharmaceutical Journal
AVERT trial demonstrates high rates of DAS-defined remission with Orencia® (abatacept) in combination with Methotrexate in adult patients with early rheumatoid arthritis - Drug Target Review
AVERT trial demonstrates high rates of DAS-defined remission with Orencia® (abatacept) in combination with Methotrexate in adult patients with early rheumatoid arthritis  Drug Target Review
'My arthritis symptoms began when I was pregnant at 23 - it was so painful I took early maternity leave' - inews
'My arthritis symptoms began when I was pregnant at 23 - it was so painful I took early maternity leave'  inews
PUTTING THE SPOTLIGHT ON RHEUMATOID ARTHRITIS - Island Echo
PUTTING THE SPOTLIGHT ON RHEUMATOID ARTHRITIS  Island Echo
Rheumatoid arthritis: Overweight and obese people at greater risk - Express
Rheumatoid arthritis: Overweight and obese people at greater risk  Express
Arthritis warning: The healthy foods that can actually trigger arthritis symptoms - Express
Arthritis warning: The healthy foods that can actually trigger arthritis symptoms  Express
New arthritis pill that can end the hell of stiff joints - Daily Mail
New arthritis pill that can end the hell of stiff joints  Daily Mail
Tendon Inflammation in the Hand Predicts Future Arthritis - Medscape
Tendon Inflammation in the Hand Predicts Future Arthritis  Medscape
COVID-19 headache location: Is headache an early symptom of coronavirus? - Express
COVID-19 headache location: Is headache an early symptom of coronavirus?  Express
Tatum O'Neal reveals her surgery scars and bruises left by rheumatoid arthritis - Daily Mail
Tatum O'Neal reveals her surgery scars and bruises left by rheumatoid arthritis  Daily Mail
Vivian P. Bykerk, BSc, MD, FRCPC - HSS | Hospital for Special Surgery
Vivian P. Bykerk, BSc, MD, FRCPC  HSS | Hospital for Special Surgery
Immune system's response to parasite eases arthritis inflammation - Daily Mail
Immune system's response to parasite eases arthritis inflammation  Daily Mail
Characteristic-specific rates of rheumatoid arthritis and its management in Australian general practice - RACGP
Characteristic-specific rates of rheumatoid arthritis and its management in Australian general practice  RACGP
Thousands of elderly people suffering with rheumatoid arthritis needlessly, say MPs - Daily Mail
Thousands of elderly people suffering with rheumatoid arthritis needlessly, say MPs  Daily Mail
England | London | Six taken ill after drug trials - CBBC Newsround
England | London | Six taken ill after drug trials  CBBC Newsround

Articles/peer reviewed publications and
Lay Summaries

  • B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure.
    Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC- R4RA investigators. 
    Arthritis Rheumatol. 2019 Nov 29.
    https://doi.org/10.1002/art.41184
    See Lay Summary




The R4-RA trial is funded by the MRC-NIHR Efficacy and
Mechanism Evaluation Programme