Highlights and News

UK leads the world in rapid activation of complex early-phase ATiMP trial - NIHR
UK leads the world in rapid activation of complex early-phase ATiMP trial  NIHR
Why Rheumatoid Arthritis Remission Rates Remain Stagnant - EMJ
Why Rheumatoid Arthritis Remission Rates Remain Stagnant  EMJ
Rheumatoid arthritis patient trial backs up vaccination advantages of methotrexate delay - thepharmacist.co.uk
Rheumatoid arthritis patient trial backs up vaccination advantages of methotrexate delay  thepharmacist.co.uk
The breakthrough that could stop arthritis and diabetes in their tracks - The i Paper
The breakthrough that could stop arthritis and diabetes in their tracks  The i Paper
New gene study offers arthritis treatment insights - HealthandCare.scot
New gene study offers arthritis treatment insights  HealthandCare.scot
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis - Wiley Online Library
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis  Wiley Online Library
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis - Nature
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis  Nature
Championing physio for inflammatory arthritis - The Chartered Society of Physiotherapy
Championing physio for inflammatory arthritis  The Chartered Society of Physiotherapy
Investigating the Impact of Sex on Outcomes in Juvenile Idiopathic Arthritis - medRxiv
Investigating the Impact of Sex on Outcomes in Juvenile Idiopathic Arthritis  medRxiv
Foot and Ankle Care in Inflammatory Arthritis - Arthritis Foundation
Foot and Ankle Care in Inflammatory Arthritis  Arthritis Foundation
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA - HealthCentral
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA  HealthCentral
First UK patient treated in ‘OSCAR' COVID-19 research study, trialling experimental arthritis drug as treatment for coronavirus - Manchester University NHS Foundation Trust
First UK patient treated in ‘OSCAR' COVID-19 research study, trialling experimental arthritis drug as treatment for coronavirus  Manchester University NHS Foundation Trust
Rheumatoid arthritis - The Lancet
Rheumatoid arthritis  The Lancet
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis - The New England Journal of Medicine
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis  The New England Journal of Medicine
Crying out for equity: outcomes of rheumatic diseases confounded by ethnicity | Clinical Rheumatology - Springer Nature Link
Crying out for equity: outcomes of rheumatic diseases confounded by ethnicity | Clinical Rheumatology  Springer Nature Link
Tight Control of Psoriatic Arthritis: Real-World Outcomes From TICOPA - Rheumatology Advisor
Tight Control of Psoriatic Arthritis: Real-World Outcomes From TICOPA  Rheumatology Advisor
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients - Nature
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients  Nature
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review - EMJ
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review  EMJ
Review of the European Alliance of Associations for Rheumatology (EULAR) 2026 Congress - EMJ
Review of the European Alliance of Associations for Rheumatology (EULAR) 2026 Congress  EMJ
Blocking the immune system in rheumatoid arthritis - The Pharmaceutical Journal
Blocking the immune system in rheumatoid arthritis  The Pharmaceutical Journal
Artificial intelligence in rheumatoid arthritis research: A bibliometric analysis from 2004 to 2023 - Wiley Online Library
Artificial intelligence in rheumatoid arthritis research: A bibliometric analysis from 2004 to 2023  Wiley Online Library
Tofacitinib versus Methotrexate in Rheumatoid Arthritis - The New England Journal of Medicine
Tofacitinib versus Methotrexate in Rheumatoid Arthritis  The New England Journal of Medicine
The N-Formyl Peptide Receptors and Rheumatoid Arthritis: A Dangerous Liaison or Confusing Relationship? - Frontiers
The N-Formyl Peptide Receptors and Rheumatoid Arthritis: A Dangerous Liaison or Confusing Relationship?  Frontiers
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission - Nature
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission  Nature
Novel biomarkers of a peripheral blood interferon signature associated with drug-naïve early arthritis patients distinguish persistent from self-limiting disease course - Nature
Novel biomarkers of a peripheral blood interferon signature associated with drug-naïve early arthritis patients distinguish persistent from self-limiting disease course  Nature
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics | Scientific Reports - Nature
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics | Scientific Reports  Nature
Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis - The New England Journal of Medicine
Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis  The New England Journal of Medicine
Meera Alagarajah on dealing with rheumatoid arthritis - Dentistry Online - Dentistry.co.uk
Meera Alagarajah on dealing with rheumatoid arthritis - Dentistry Online  Dentistry.co.uk
Treatment of Rheumatoid Arthritis by Selective Inhibition of T-Cell Activation with Fusion Protein CTLA4Ig - The New England Journal of Medicine
Treatment of Rheumatoid Arthritis by Selective Inhibition of T-Cell Activation with Fusion Protein CTLA4Ig  The New England Journal of Medicine
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure - The New England Journal of Medicine
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure  The New England Journal of Medicine
Quell launches chill phase 1/2 trial for novel cartreg therapy - PharmaTimes
Quell launches chill phase 1/2 trial for novel cartreg therapy  PharmaTimes
Understanding rheumatoid arthritis at the cellular level - National Institutes of Health (NIH) | (.gov)
Understanding rheumatoid arthritis at the cellular level  National Institutes of Health (NIH) | (.gov)
Rheumatoid arthritis - Nature
Rheumatoid arthritis  Nature
Rheumatoid Arthritis: GLP-1 Drugs Like Ozempic May Decrease Flare-Ups - Healthline
Rheumatoid Arthritis: GLP-1 Drugs Like Ozempic May Decrease Flare-Ups  Healthline
Rheumatoid arthritis and baking soda: The potential benefits - Medical News Today
Rheumatoid arthritis and baking soda: The potential benefits  Medical News Today
Ibuprofen for arthritis: Is it safe to take every day? - Medical News Today
Ibuprofen for arthritis: Is it safe to take every day?  Medical News Today
Treating rheumatoid arthritis with JAK inhibitors: What to know - Medical News Today
Treating rheumatoid arthritis with JAK inhibitors: What to know  Medical News Today
PEPITEM 'replacement therapy' shows potential for early-stage inflammatory arthritis - Medical Xpress
PEPITEM 'replacement therapy' shows potential for early-stage inflammatory arthritis  Medical Xpress
Rheumatoid arthritis cure: Is it possible? - Medical News Today
Rheumatoid arthritis cure: Is it possible?  Medical News Today
Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients | Scientific Reports - Nature
Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients | Scientific Reports  Nature
New drug Bimzelx shows promise as a treatment for psoriatic arthritis - Medical News Today
New drug Bimzelx shows promise as a treatment for psoriatic arthritis  Medical News Today
Integrating point-of-care ultrasound into rheumatology practice - Medycyna Praktyczna
Integrating point-of-care ultrasound into rheumatology practice  Medycyna Praktyczna
Rheumatoid arthritis: Could a test tell which biologic may be best? - Medical News Today
Rheumatoid arthritis: Could a test tell which biologic may be best?  Medical News Today
Turmeric for rheumatoid arthritis: Does it work? - Medical News Today
Turmeric for rheumatoid arthritis: Does it work?  Medical News Today
Weather, seasons, and rheumatoid arthritis flares - Medical News Today
Weather, seasons, and rheumatoid arthritis flares  Medical News Today
Rheumatoid Arthritis: Common Questions About Diagnosis and Management - American Academy Of Family Physicians | AAFP
Rheumatoid Arthritis: Common Questions About Diagnosis and Management  American Academy Of Family Physicians | AAFP
Treatments for rheumatoid arthritis: Traditional DMARDS vs. biologics - Medical News Today
Treatments for rheumatoid arthritis: Traditional DMARDS vs. biologics  Medical News Today
Minocycline for rheumatoid arthritis: What to know - Medical News Today
Minocycline for rheumatoid arthritis: What to know  Medical News Today
What to know about rheumatoid arthritis and intermittent fasting - Medical News Today
What to know about rheumatoid arthritis and intermittent fasting  Medical News Today
Hydroxychloroquine for rheumatoid arthritis: Uses and more - Medical News Today
Hydroxychloroquine for rheumatoid arthritis: Uses and more  Medical News Today
Blood test could provide an early arthritis warning - Nursing Times
Blood test could provide an early arthritis warning  Nursing Times
U.K. approves anti-inflammatory drugs to treat sickest covid-19 patients after strong results in clinical trial - The Washington Post
U.K. approves anti-inflammatory drugs to treat sickest covid-19 patients after strong results in clinical trial  The Washington Post
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis - The New England Journal of Medicine
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis  The New England Journal of Medicine
Breakthrough cell therapy could replace organ transplants - and save NHS millions - The i Paper
Breakthrough cell therapy could replace organ transplants - and save NHS millions  The i Paper
Advances in the Treatment of Early Rheumatoid Arthritis - American Academy Of Family Physicians | AAFP
Advances in the Treatment of Early Rheumatoid Arthritis  American Academy Of Family Physicians | AAFP
Ankylosing spondylitis: an update - Royal Australian College of General Practitioners (RACGP)
Ankylosing spondylitis: an update  Royal Australian College of General Practitioners (RACGP)
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis - The New England Journal of Medicine
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis  The New England Journal of Medicine
Chinese herbal remedy 'just as effective as methotrexate against arthritis' - Medical News Today
Chinese herbal remedy 'just as effective as methotrexate against arthritis'  Medical News Today
England | London | Six taken ill after drug trials - BBC
England | London | Six taken ill after drug trials  BBC
From a sensitive scalp to voice changes - the hidden warning signs arthritis is creeping up on you - The Sun
From a sensitive scalp to voice changes - the hidden warning signs arthritis is creeping up on you  The Sun

Articles/peer reviewed publications and
Lay Summaries

  • B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure.
    Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC- R4RA investigators. 
    Arthritis Rheumatol. 2019 Nov 29.
    https://doi.org/10.1002/art.41184
    See Lay Summary




The R4-RA trial is funded by the MRC-NIHR Efficacy and
Mechanism Evaluation Programme