Highlights and News

Comparison of surgery rates in biologic-naïve patients with Crohn's ... - BMC Gastroenterology
Comparison of surgery rates in biologic-naïve patients with Crohn's ...  BMC Gastroenterology
Approaches to optimising access to NICE-approved biologic anti ... - BMC Medicine
Approaches to optimising access to NICE-approved biologic anti ...  BMC Medicine
Incidence and management of inflammatory arthritis in England ... - The Lancet
Incidence and management of inflammatory arthritis in England ...  The Lancet
Study finds an increase in the proportion of adults in England diagnosed with inflammatory arthritis - News-Medical.Net
Study finds an increase in the proportion of adults in England diagnosed with inflammatory arthritis  News-Medical.Net
Early Signs And Symptoms Of Arthritis - Forbes Health - Forbes
Early Signs And Symptoms Of Arthritis - Forbes Health  Forbes
Adalimumab is found to be a cost-effective treatment for early-stage ... - Nuffield Department of Population Health
Adalimumab is found to be a cost-effective treatment for early-stage ...  Nuffield Department of Population Health
RA-MAP, molecular immunological landscapes in early rheumatoid ... - Nature.com
RA-MAP, molecular immunological landscapes in early rheumatoid ...  Nature.com
GSK provides update on ContRAst phase III programme for otilimab ... - GSK
GSK provides update on ContRAst phase III programme for otilimab ...  GSK
Associations of rheumatoid arthritis and rheumatoid factor with ... - Nature.com
Associations of rheumatoid arthritis and rheumatoid factor with ...  Nature.com
The probiotics that make drugs inside your body - Daily Mail
The probiotics that make drugs inside your body  Daily Mail
Highest-risk patients eligible for new COVID-19 treatments: a guide ... - GOV.UK
Highest-risk patients eligible for new COVID-19 treatments: a guide ...  GOV.UK
WTF? What is the future? - Dentistry - Dentistry.co.uk
WTF? What is the future? - Dentistry  Dentistry.co.uk
Advances in Rheumatoid Arthritis Treatment Improves Quality of Life - Health Central
Advances in Rheumatoid Arthritis Treatment Improves Quality of Life  Health Central
Scientists hail autoimmune disease therapy breakthrough - The Guardian
Scientists hail autoimmune disease therapy breakthrough  The Guardian
Is Rheumatoid Arthritis Genetic or Hereditary? - Health Central
Is Rheumatoid Arthritis Genetic or Hereditary?  Health Central
Integrated single cell and spatial transcriptomics reveal autoreactive ... - Nature.com
Integrated single cell and spatial transcriptomics reveal autoreactive ...  Nature.com
Olokizumab versus Placebo or Adalimumab in Rheumatoid Arthritis ... - nejm.org
Olokizumab versus Placebo or Adalimumab in Rheumatoid Arthritis ...  nejm.org
Early onset of immune-mediated diseases in minority ethnic groups ... - BMC Medicine
Early onset of immune-mediated diseases in minority ethnic groups ...  BMC Medicine
Natural Remedies for Rheumatoid Arthritis - Health Essentials
Natural Remedies for Rheumatoid Arthritis  Health Essentials
Treatments for COVID-19 - NHS Website
Treatments for COVID-19  NHS Website
Pain intensity correlates with disease activity in RA - Medicine Matters rheumatology
Pain intensity correlates with disease activity in RA  Medicine Matters rheumatology
The burden of rheumatoid arthritis in the Middle East and North ... - Nature.com
The burden of rheumatoid arthritis in the Middle East and North ...  Nature.com
Multimorbidity May Increase Risk, Duration of Hospitalization for ... - AJMC.com Managed Markets Network
Multimorbidity May Increase Risk, Duration of Hospitalization for ...  AJMC.com Managed Markets Network
Chapter 9: pharmaceutical interventions: therapeutics and vaccines - GOV.UK
Chapter 9: pharmaceutical interventions: therapeutics and vaccines  GOV.UK
Steroid injections may make arthritis WORSE, studies show - Daily Mail
Steroid injections may make arthritis WORSE, studies show  Daily Mail
Osteoarthritis: New Drug May Help Stop Symptoms - Healthline
Osteoarthritis: New Drug May Help Stop Symptoms  Healthline
Study: Olokinzumab As Effective as "Gold Standard” Treatment for ... - Pharmacy Times
Study: Olokinzumab As Effective as "Gold Standard” Treatment for ...  Pharmacy Times
The anti-inflammatory drug that could reverse the aging process - Daily Mail
The anti-inflammatory drug that could reverse the aging process  Daily Mail
Defining the highest-risk clinical subgroups upon community ... - GOV.UK
Defining the highest-risk clinical subgroups upon community ...  GOV.UK
Midfoot arthritis: Symptoms, causes, and treatment - Medical News Today
Midfoot arthritis: Symptoms, causes, and treatment  Medical News Today
MHRA approves first oral advanced therapy for Crohn's disease - European Pharmaceutical Review
MHRA approves first oral advanced therapy for Crohn's disease  European Pharmaceutical Review
New breakthrough in the treatment of rheumatoid arthritis - University of Birmingham
New breakthrough in the treatment of rheumatoid arthritis  University of Birmingham
X-Rays and Medical Imaging for Arthritis Diagnosis - Health Central
X-Rays and Medical Imaging for Arthritis Diagnosis  Health Central
UK medicine regulator considering safety measures for JAK ... - The Pharmaceutical Journal
UK medicine regulator considering safety measures for JAK ...  The Pharmaceutical Journal
Living with rheumatoid arthritis: 'I've only ever known pain and fatigue' - inews
Living with rheumatoid arthritis: 'I've only ever known pain and fatigue'  inews
All or something: Experts debate LDA vs. remission as a target in ... - Healio
All or something: Experts debate LDA vs. remission as a target in ...  Healio
Bimekizumab in patients with psoriatic arthritis, naive to biologic ... - The Lancet
Bimekizumab in patients with psoriatic arthritis, naive to biologic ...  The Lancet
Rheumatoid arthritis in knees: Pictures, symptoms, and more - Medical News Today
Rheumatoid arthritis in knees: Pictures, symptoms, and more  Medical News Today
Common workplace fumes and dusts may heighten rheumatoid ... - The BMJ
Common workplace fumes and dusts may heighten rheumatoid ...  The BMJ
Rheumatologist for psoriatic arthritis: How they can help - Medical News Today
Rheumatologist for psoriatic arthritis: How they can help  Medical News Today
Diet unlikely to ease progression of osteoarthritis, rheumatoid ... - The BMJ
Diet unlikely to ease progression of osteoarthritis, rheumatoid ...  The BMJ
Rheumatoid arthritis in the hip: Symptoms and management - Medical News Today
Rheumatoid arthritis in the hip: Symptoms and management  Medical News Today
Frailty may be reversible for some people with rheumatoid arthritis - Medical Xpress
Frailty may be reversible for some people with rheumatoid arthritis  Medical Xpress
Rheumatoid Arthritis Flare-Ups: Symptoms, Causes, Coping - Verywell Health
Rheumatoid Arthritis Flare-Ups: Symptoms, Causes, Coping  Verywell Health
Rheumatoid arthritis in hands: Stage 1, progression, and more - Medical News Today
Rheumatoid arthritis in hands: Stage 1, progression, and more  Medical News Today
Can arthritis be reversed? - Medical News Today
Can arthritis be reversed?  Medical News Today
Arthritis in the Hips: Symptoms, Types of Hip Arthritis, Treatment - CreakyJoints
Arthritis in the Hips: Symptoms, Types of Hip Arthritis, Treatment  CreakyJoints
What Runners Should Know About Running and Rheumatoid Arthritis - Runner's World
What Runners Should Know About Running and Rheumatoid Arthritis  Runner's World
Rheumatoid Arthritis Differential Diagnosis - Verywell Health
Rheumatoid Arthritis Differential Diagnosis  Verywell Health
10+ Early Signs and Symptoms of Rheumatoid Arthritis - Verywell Health
10+ Early Signs and Symptoms of Rheumatoid Arthritis  Verywell Health
Arthritis in the Back: Symptoms, Types of Back Arthritis, Treatment - CreakyJoints
Arthritis in the Back: Symptoms, Types of Back Arthritis, Treatment  CreakyJoints
Claim PIP for 87 muscle or joint conditions and you could get up to £156 each week tax-free - Daily Record
Claim PIP for 87 muscle or joint conditions and you could get up to £156 each week tax-free  Daily Record
Rheumatoid Arthritis Not Responding to Treatment: - Verywell Health
Rheumatoid Arthritis Not Responding to Treatment:  Verywell Health
Rheumatology - University College London Hospitals
Rheumatology  University College London Hospitals
Interrupting immune-suppressing treatment can boost COVID vaccine response - Imperial College London
Interrupting immune-suppressing treatment can boost COVID vaccine response  Imperial College London
Covid-19: surging demand for some arthritis drugs - The BMJ
Covid-19: surging demand for some arthritis drugs  The BMJ
Exercise and weight-loss are key to combating crippling arthritis, health watchdog says - Daily Mail
Exercise and weight-loss are key to combating crippling arthritis, health watchdog says  Daily Mail
Understanding hip arthritis: risk factors, symptoms and treatments - Spire Healthcare
Understanding hip arthritis: risk factors, symptoms and treatments  Spire Healthcare
Rheumatoid Arthritis Progression: Tests That Track Activity - Verywell Health
Rheumatoid Arthritis Progression: Tests That Track Activity  Verywell Health
Criteria to Diagnose Rheumatoid Arthritis: What Patients Need to ... - CreakyJoints
Criteria to Diagnose Rheumatoid Arthritis: What Patients Need to ...  CreakyJoints
Ways physical therapy can alleviate arthritis pain - Medical News Today
Ways physical therapy can alleviate arthritis pain  Medical News Today
New and FDA-Approved Treatments for Alopecia Areata - Healthline
New and FDA-Approved Treatments for Alopecia Areata  Healthline
Dry eye - RNIB
Dry eye  RNIB
Arthritis treatment which can help patients with alopecia - Daily Mail
Arthritis treatment which can help patients with alopecia  Daily Mail
Rheumatology - St George's University Hospitals NHS Foundation Trust
Rheumatology  St George's University Hospitals NHS Foundation Trust
Research reveals that anti-TNF drug reverses Dupuytren's disease - Open Access Government
Research reveals that anti-TNF drug reverses Dupuytren's disease  Open Access Government
"There isn't anything like it in the UK" - University of Cambridge news
"There isn't anything like it in the UK"  University of Cambridge news
Steroids for Rheumatic Disease and Regional Pain Disorders - PracticalPainManagement.com
Steroids for Rheumatic Disease and Regional Pain Disorders  PracticalPainManagement.com
Inflammatory Arthritis: Latest Advances in Treatment - hss.edu
Inflammatory Arthritis: Latest Advances in Treatment  hss.edu
Hip pain at night (sleeping): causes and symptoms - Spire Healthcare
Hip pain at night (sleeping): causes and symptoms  Spire Healthcare
Doctors and pharmacists have started refusing US women pain ... - inews
Doctors and pharmacists have started refusing US women pain ...  inews
Hydroxychloroquine, chloroquine: increased risk of cardiovascular ... - GOV.UK
Hydroxychloroquine, chloroquine: increased risk of cardiovascular ...  GOV.UK
COVID-19: guidance for people whose immune system means they ... - GOV.UK
COVID-19: guidance for people whose immune system means they ...  GOV.UK
Rheumatoid arthritis in the wrist: Symptoms, treatment, and exercises - Medical News Today
Rheumatoid arthritis in the wrist: Symptoms, treatment, and exercises  Medical News Today
Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid ... - nejm.org
Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid ...  nejm.org
Rheumatoid arthritis (RA): Symptoms, treatments, causes, and more - Medical News Today
Rheumatoid arthritis (RA): Symptoms, treatments, causes, and more  Medical News Today
Arthritis drug effective in treating sickest COVID-19 patients - Imperial College London
Arthritis drug effective in treating sickest COVID-19 patients  Imperial College London
Comparative effectiveness of biological medicines in rheumatoid ... - The BMJ
Comparative effectiveness of biological medicines in rheumatoid ...  The BMJ
Rheumatoid Arthritis Symptoms, Signs & Causes - Spire Healthcare
Rheumatoid Arthritis Symptoms, Signs & Causes  Spire Healthcare
Rheumatoid arthritis: How does it affect the elbow? - Medical News Today
Rheumatoid arthritis: How does it affect the elbow?  Medical News Today
Rheumatoid Arthritis Nail Changes: Ridges, Yellowing, and More - Healthline
Rheumatoid Arthritis Nail Changes: Ridges, Yellowing, and More  Healthline
8 Early Signs of Arthritis You Should Never Ignore - AARP
8 Early Signs of Arthritis You Should Never Ignore  AARP
Rheumatoid Arthritis in Elbow: Symptoms, Treatments, and More - Healthline
Rheumatoid Arthritis in Elbow: Symptoms, Treatments, and More  Healthline
Gout | NEJM - nejm.org
Gout | NEJM  nejm.org
Osteoarthritis in the foot: Symptoms and how to manage it - Medical News Today
Osteoarthritis in the foot: Symptoms and how to manage it  Medical News Today
Common types of arthritis: Location, causes, treatment, and more - Medical News Today
Common types of arthritis: Location, causes, treatment, and more  Medical News Today
Rheumatoid arthritis vs. osteoarthritis: What's the difference? - Medical News Today
Rheumatoid arthritis vs. osteoarthritis: What's the difference?  Medical News Today
Long COVID, FibroCOVID, and Musculoskeletal Pain: Why Pre ... - PracticalPainManagement.com
Long COVID, FibroCOVID, and Musculoskeletal Pain: Why Pre ...  PracticalPainManagement.com
Trial suggests JAK1 inhibitor is superior to methotrexate for ... - The Pharmaceutical Journal
Trial suggests JAK1 inhibitor is superior to methotrexate for ...  The Pharmaceutical Journal
10 Unusual Symptoms of Rheumatoid Arthritis and Why They Occur - Healthline
10 Unusual Symptoms of Rheumatoid Arthritis and Why They Occur  Healthline
Covid-19: Evusheld is approved in UK for prophylaxis in ... - The BMJ
Covid-19: Evusheld is approved in UK for prophylaxis in ...  The BMJ
Mosaic Turner Syndrome: What It Is and How It's Treated - Healthline
Mosaic Turner Syndrome: What It Is and How It's Treated  Healthline
COVID-19 can ruin your sleep in many different ways-here's why - National Geographic UK
COVID-19 can ruin your sleep in many different ways-here's why  National Geographic UK
Rheumatoid arthritis and gastrointestinal symptoms: Causes and more - Medical News Today
Rheumatoid arthritis and gastrointestinal symptoms: Causes and more  Medical News Today
Arthritis drugs may reduce mortality and time in ICU for sickest COVID patients - Imperial College London
Arthritis drugs may reduce mortality and time in ICU for sickest COVID patients  Imperial College London
Experimental vaccine a major breakthrough for rheumatoid arthritis - Drug Target Review
Experimental vaccine a major breakthrough for rheumatoid arthritis  Drug Target Review
Targeting synovial fibroblast proliferation in rheumatoid arthritis ... - The Lancet
Targeting synovial fibroblast proliferation in rheumatoid arthritis ...  The Lancet
Rheumatoid nodules: Symptoms, causes, and pictures - Medical News Today
Rheumatoid nodules: Symptoms, causes, and pictures  Medical News Today
Psoriatic Arthritis Early Signs: 11 Signs and Symptoms to Watch For - Healthline
Psoriatic Arthritis Early Signs: 11 Signs and Symptoms to Watch For  Healthline

Articles/peer reviewed publications and
Lay Summaries

  • B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure.
    Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC- R4RA investigators. 
    Arthritis Rheumatol. 2019 Nov 29.
    https://doi.org/10.1002/art.41184
    See Lay Summary




The R4-RA trial is funded by the MRC-NIHR Efficacy and
Mechanism Evaluation Programme