Highlights and News

Pain intensity correlates with disease activity in RA - Medicine Matters rheumatology
Pain intensity correlates with disease activity in RA  Medicine Matters rheumatology
Galapagos provides further insights into the treatment of ulcerative colitis at the upcoming United European Gastroenterology (UEG) Week 2022 congress - Yahoo Finance
Galapagos provides further insights into the treatment of ulcerative colitis at the upcoming United European Gastroenterology (UEG) Week 2022 congress  Yahoo Finance
Is Rheumatoid Arthritis Genetic or Hereditary? - Health Central
Is Rheumatoid Arthritis Genetic or Hereditary?  Health Central
Humira Explained: Usage, Dosage, And Side Effects - Health Digest
Humira Explained: Usage, Dosage, And Side Effects  Health Digest
Treatments for coronavirus (COVID-19) - NHS Website
Treatments for coronavirus (COVID-19)  NHS Website
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients | Scientific Data - Nature.com
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients | Scientific Data  Nature.com
Treatment for finger-bending disease may be ‘gamechanger' - The Guardian
Treatment for finger-bending disease may be ‘gamechanger'  The Guardian
Highest-risk patients eligible for new COVID-19 treatments: a guide for patients - GOV.UK
Highest-risk patients eligible for new COVID-19 treatments: a guide for patients  GOV.UK
Frailty may be reversible for some people with rheumatoid arthritis - Medical Xpress
Frailty may be reversible for some people with rheumatoid arthritis  Medical Xpress
Defining the highest-risk clinical subgroups upon community infection with SARS-CoV-2 when considering the use of neutralising monoclonal antibodies (nMABs) and antiviral drugs: independent advisory group report - GOV.UK
Defining the highest-risk clinical subgroups upon community infection with SARS-CoV-2 when considering the use of neutralising monoclonal antibodies (nMABs) and antiviral drugs: independent advisory group report  GOV.UK
All or something: Experts debate LDA vs. remission as a target in rheumatoid arthritis - Healio
All or something: Experts debate LDA vs. remission as a target in rheumatoid arthritis  Healio
Frailty common in rheumatoid arthritis, predicts mortality, hospitalization - Healio
Frailty common in rheumatoid arthritis, predicts mortality, hospitalization  Healio
Effective New Drug Could Expand Treatment Options for Rheumatoid Arthritis - Technology Networks
Effective New Drug Could Expand Treatment Options for Rheumatoid Arthritis  Technology Networks
Urica Therapeutics Appoints Seasoned Biotech Executive Jay D. Kranzler, MD, Ph.D., as Chairman and Chief Executive Officer - GlobeNewswire
Urica Therapeutics Appoints Seasoned Biotech Executive Jay D. Kranzler, MD, Ph.D., as Chairman and Chief Executive Officer  GlobeNewswire
Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial - The Lancet
Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial  The Lancet
US anti-abortion laws may restrict access to vital drug for autoimmune diseases, patient groups warn - The BMJ
US anti-abortion laws may restrict access to vital drug for autoimmune diseases, patient groups warn  The BMJ
New breakthrough in the treatment of rheumatoid arthritis - University of Birmingham
New breakthrough in the treatment of rheumatoid arthritis  University of Birmingham
Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform - The Lancet
Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform  The Lancet
Diet unlikely to ease progression of osteoarthritis, rheumatoid arthritis | BMJ - The BMJ
Diet unlikely to ease progression of osteoarthritis, rheumatoid arthritis | BMJ  The BMJ
COVID-19: guidance for people whose immune system means they are at higher risk - GOV.UK
COVID-19: guidance for people whose immune system means they are at higher risk  GOV.UK
X-Rays and Medical Imaging for Arthritis Diagnosis - Health Central
X-Rays and Medical Imaging for Arthritis Diagnosis  Health Central
Understanding hip arthritis: risk factors, symptoms and treatments - Spire Healthcare
Understanding hip arthritis: risk factors, symptoms and treatments  Spire Healthcare
Rheumatoid arthritis in hands: Stage 1, progression, and more - Medical News Today
Rheumatoid arthritis in hands: Stage 1, progression, and more  Medical News Today
Rheumatoid arthritis and the eyes: Impact and symptoms - Medical News Today
Rheumatoid arthritis and the eyes: Impact and symptoms  Medical News Today
SILO PROFILE - Insider Financial
SILO PROFILE  Insider Financial
11 early rheumatoid arthritis signs including fatigue and weight loss - Glasgow Live
11 early rheumatoid arthritis signs including fatigue and weight loss  Glasgow Live
10+ Early Signs and Symptoms of Rheumatoid Arthritis - Verywell Health
10+ Early Signs and Symptoms of Rheumatoid Arthritis  Verywell Health
Hydroxychloroquine or chloroquine, in combination with macrolide antibiotics: review of epidemiological data for cardiovascular safety - GOV.UK
Hydroxychloroquine or chloroquine, in combination with macrolide antibiotics: review of epidemiological data for cardiovascular safety  GOV.UK
Midfoot arthritis: Symptoms, causes, and treatment - Medical News Today
Midfoot arthritis: Symptoms, causes, and treatment  Medical News Today
Country policy and information note: medical treatment and healthcare, China, July 2022 (accessible) - GOV.UK
Country policy and information note: medical treatment and healthcare, China, July 2022 (accessible)  GOV.UK
Integrated single cell and spatial transcriptomics reveal autoreactive differentiated B cells in joints of early rheumatoid arthritis | Scientific Reports - Nature.com
Integrated single cell and spatial transcriptomics reveal autoreactive differentiated B cells in joints of early rheumatoid arthritis | Scientific Reports  Nature.com
Exercise could combat fatigue among arthritis patients says Scottish study - Edinburgh Live
Exercise could combat fatigue among arthritis patients says Scottish study  Edinburgh Live
Steroids for Rheumatic Disease and Regional Pain Disorders - PracticalPainManagement.com
Steroids for Rheumatic Disease and Regional Pain Disorders  PracticalPainManagement.com
Covid-19: surging demand for some arthritis drugs - The BMJ
Covid-19: surging demand for some arthritis drugs  The BMJ
Hydroxychloroquine, chloroquine: increased risk of cardiovascular events when used with macrolide antibiotics; reminder of psychiatric reactions - GOV.UK
Hydroxychloroquine, chloroquine: increased risk of cardiovascular events when used with macrolide antibiotics; reminder of psychiatric reactions  GOV.UK
Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis | NEJM - nejm.org
Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis | NEJM  nejm.org
Rheumatoid Arthritis Differential Diagnosis - Verywell Health
Rheumatoid Arthritis Differential Diagnosis  Verywell Health
Rheumatologist for psoriatic arthritis: How they can help - Medical News Today
Rheumatologist for psoriatic arthritis: How they can help  Medical News Today
Research reveals that anti-TNF drug reverses Dupuytren's disease - Open Access Government
Research reveals that anti-TNF drug reverses Dupuytren's disease  Open Access Government
Fatigue common even with early rheumatoid arthritis - Medical Xpress
Fatigue common even with early rheumatoid arthritis  Medical Xpress
Can arthritis be reversed? - Medical News Today
Can arthritis be reversed?  Medical News Today
'Milestone' as NICE recommends biologics in moderate rheumatoid arthritis for the first time - The Pharmaceutical Journal
'Milestone' as NICE recommends biologics in moderate rheumatoid arthritis for the first time  The Pharmaceutical Journal
Natural treatments for osteoarthritis - Medical News Today
Natural treatments for osteoarthritis  Medical News Today
Rheumatoid Arthritis Progression: Tests That Track Activity - Verywell Health
Rheumatoid Arthritis Progression: Tests That Track Activity  Verywell Health
Hip pain at night (sleeping): causes and symptoms - Spire Healthcare
Hip pain at night (sleeping): causes and symptoms  Spire Healthcare
Covid: Arthritis-like symptoms could be sign of Omicron infection as UK cases surge - Express
Covid: Arthritis-like symptoms could be sign of Omicron infection as UK cases surge  Express

Articles/peer reviewed publications and
Lay Summaries

  • B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure.
    Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC- R4RA investigators. 
    Arthritis Rheumatol. 2019 Nov 29.
    https://doi.org/10.1002/art.41184
    See Lay Summary




The R4-RA trial is funded by the MRC-NIHR Efficacy and
Mechanism Evaluation Programme