Highlights and News

New gene study offers arthritis treatment insights - HealthandCare.scot
New gene study offers arthritis treatment insights  HealthandCare.scot
Methotrexate oral or subcutaneous for rheumatoid arthritis (MOOSE): study protocol for a multi-centre randomised trial - Springer Nature Link
Methotrexate oral or subcutaneous for rheumatoid arthritis (MOOSE): study protocol for a multi-centre randomised trial  Springer Nature Link
New research reveals shared genetic link between endometriosis and immune conditions - University of Oxford
New research reveals shared genetic link between endometriosis and immune conditions  University of Oxford
Is There a Missing Link in Rheumatoid Arthritis Management? - EMJ
Is There a Missing Link in Rheumatoid Arthritis Management?  EMJ
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis - Wiley Online Library
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis  Wiley Online Library
Links between arthritis therapy and heart disease improvements - University of Leeds
Links between arthritis therapy and heart disease improvements  University of Leeds
Biological treatment in rheumatoid arthritis: when to stop? - The Lancet
Biological treatment in rheumatoid arthritis: when to stop?  The Lancet
Impact of Rheumatoid Arthritis and Its Management on Falls, Fracture and Bone Mineral Density in UK Biobank - Frontiers
Impact of Rheumatoid Arthritis and Its Management on Falls, Fracture and Bone Mineral Density in UK Biobank  Frontiers
Refractory Inflammatory Arthritis definition and model generated through patient and multi-disciplinary professional modified Delphi process - medRxiv
Refractory Inflammatory Arthritis definition and model generated through patient and multi-disciplinary professional modified Delphi process  medRxiv
Study finds new treatment to reverse inflammation and arterial blockages in rheumatoid arthritis - Queen Mary University of London
Study finds new treatment to reverse inflammation and arterial blockages in rheumatoid arthritis  Queen Mary University of London
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial - Nature
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial  Nature
Understanding Methotrexate - Arthritis Foundation
Understanding Methotrexate  Arthritis Foundation
First UK patient treated in ‘OSCAR' COVID-19 research study, trialling experimental arthritis drug as treatment for coronavirus - Manchester University NHS Foundation Trust
First UK patient treated in ‘OSCAR' COVID-19 research study, trialling experimental arthritis drug as treatment for coronavirus  Manchester University NHS Foundation Trust
Rheumatoid Arthritis Life Expectancy: What You Need to Know - HealthCentral
Rheumatoid Arthritis Life Expectancy: What You Need to Know  HealthCentral
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review - EMJ
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review  EMJ
Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY - The Lancet
Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY  The Lancet
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients - Nature
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients  Nature
Foot and Ankle Care in Inflammatory Arthritis - Arthritis Foundation
Foot and Ankle Care in Inflammatory Arthritis  Arthritis Foundation
Rheumatoid arthritis - The Lancet
Rheumatoid arthritis  The Lancet
Rheumatoid arthritis diagnosis and management: a clinical update - Nursing Times
Rheumatoid arthritis diagnosis and management: a clinical update  Nursing Times
Blocking the immune system in rheumatoid arthritis - The Pharmaceutical Journal
Blocking the immune system in rheumatoid arthritis  The Pharmaceutical Journal
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis - The New England Journal of Medicine
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis  The New England Journal of Medicine
Tight Control of Psoriatic Arthritis: Real-World Outcomes From TICOPA - Rheumatology Advisor
Tight Control of Psoriatic Arthritis: Real-World Outcomes From TICOPA  Rheumatology Advisor
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA - HealthCentral
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA  HealthCentral
Moderate Psoriatic Arthritis and Perspectives from Phosphodiesterase-4 Inhibition - EMJ
Moderate Psoriatic Arthritis and Perspectives from Phosphodiesterase-4 Inhibition  EMJ
Osteoarthritis - World Health Organization (WHO)
Osteoarthritis  World Health Organization (WHO)
Rheumatoid Arthritis & Jaw Pain: Here's How to Deal - HealthCentral
Rheumatoid Arthritis & Jaw Pain: Here's How to Deal  HealthCentral
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission - Nature
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission  Nature
Efficacy of B-Cell-Targeted Therapy with Rituximab in Patients with Rheumatoid Arthritis - The New England Journal of Medicine
Efficacy of B-Cell-Targeted Therapy with Rituximab in Patients with Rheumatoid Arthritis  The New England Journal of Medicine
Association between obesity and remission in rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs | Scientific Reports - Nature
Association between obesity and remission in rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs | Scientific Reports  Nature
Rheumatoid arthritis cure: Is it possible? - Medical News Today
Rheumatoid arthritis cure: Is it possible?  Medical News Today
Novel biomarkers of a peripheral blood interferon signature associated with drug-naïve early arthritis patients distinguish persistent from self-limiting disease course | Scientific Reports - Nature
Novel biomarkers of a peripheral blood interferon signature associated with drug-naïve early arthritis patients distinguish persistent from self-limiting disease course | Scientific Reports  Nature
Psoriatic Arthritis in the Ankle: Could Your Ankle Pain Be a Sign of Psoriatic Arthritis? - CreakyJoints
Psoriatic Arthritis in the Ankle: Could Your Ankle Pain Be a Sign of Psoriatic Arthritis?  CreakyJoints
Rheumatoid arthritis and baking soda: The potential benefits - Medical News Today
Rheumatoid arthritis and baking soda: The potential benefits  Medical News Today
Rheumatoid arthritis begins years before symptoms, study finds - Medical News Today
Rheumatoid arthritis begins years before symptoms, study finds  Medical News Today
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure - The New England Journal of Medicine
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure  The New England Journal of Medicine
Osteoarthritis in primary care: early diagnosis and management - GPonline
Osteoarthritis in primary care: early diagnosis and management  GPonline
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics - Nature
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics  Nature
Exercises to improve function of the rheumatoid hand (SARAH): a randomised controlled trial - The Lancet
Exercises to improve function of the rheumatoid hand (SARAH): a randomised controlled trial  The Lancet
Rheumatoid arthritis - Nature
Rheumatoid arthritis  Nature
Psoriasis - nhs.uk
Psoriasis  nhs.uk
Tocilizumab - a new treatment for severe juvenile idiopathic arthritis in children | Research Impact - UCL - University College London
Tocilizumab - a new treatment for severe juvenile idiopathic arthritis in children | Research Impact - UCL  University College London
Is Vagus Nerve Stimulation the Future for RA Treatment? - HealthCentral
Is Vagus Nerve Stimulation the Future for RA Treatment?  HealthCentral
New drug Bimzelx shows promise as a treatment for psoriatic arthritis - Medical News Today
New drug Bimzelx shows promise as a treatment for psoriatic arthritis  Medical News Today
Early Treatment Boosts Long-term Rheumatoid Arthritis Outcomes - Medscape
Early Treatment Boosts Long-term Rheumatoid Arthritis Outcomes  Medscape
A New Study Sheds Light on the Early Roots of RA - HealthCentral
A New Study Sheds Light on the Early Roots of RA  HealthCentral
Carriers of HLA-DRB1*04:05 have a better clinical response to abatacept in rheumatoid arthritis - Nature
Carriers of HLA-DRB1*04:05 have a better clinical response to abatacept in rheumatoid arthritis  Nature
What Happens at the First Appointment With a Rheumatologist? - Everyday Health
What Happens at the First Appointment With a Rheumatologist?  Everyday Health
22 natural treatments for psoriatic arthritis - Medical News Today
22 natural treatments for psoriatic arthritis  Medical News Today
Early intensive treatment of rheumatoid arthritis offers an opportunity to manage fatigue - News-Medical
Early intensive treatment of rheumatoid arthritis offers an opportunity to manage fatigue  News-Medical
Pharmaceutical care in rheumatoid arthritis - Hospital Pharmacy Europe
Pharmaceutical care in rheumatoid arthritis  Hospital Pharmacy Europe
8 Signs of Arthritis You Shouldn't Ignore - AARP
8 Signs of Arthritis You Shouldn't Ignore  AARP
"A very Cambridge story" - University of Cambridge
"A very Cambridge story"  University of Cambridge
Treating rheumatoid arthritis with JAK inhibitors: What to know - Medical News Today
Treating rheumatoid arthritis with JAK inhibitors: What to know  Medical News Today
Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients | Scientific Reports - Nature
Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients | Scientific Reports  Nature
Ibuprofen for arthritis: Is it safe to take every day? - Medical News Today
Ibuprofen for arthritis: Is it safe to take every day?  Medical News Today
Arthritis: The sign in your cheek that could predict your risk years in advance - Daily Express
Arthritis: The sign in your cheek that could predict your risk years in advance  Daily Express
Rheumatoid arthritis: Could a test tell which biologic may be best? - Medical News Today
Rheumatoid arthritis: Could a test tell which biologic may be best?  Medical News Today
Rheumatoid arthritis: Early menopause among factors for higher risk - Medical News Today
Rheumatoid arthritis: Early menopause among factors for higher risk  Medical News Today
Rheumatoid arthritis: How to spot arthritis bumps - location and size - Daily Express
Rheumatoid arthritis: How to spot arthritis bumps - location and size  Daily Express
Early Menopause, Hormone Replacement Therapy May Raise Rheumatoid Arthritis Risk - Healthline
Early Menopause, Hormone Replacement Therapy May Raise Rheumatoid Arthritis Risk  Healthline
Turmeric for rheumatoid arthritis: Does it work? - Medical News Today
Turmeric for rheumatoid arthritis: Does it work?  Medical News Today
Arthritis drug could also help combat ovarian cancer - Nursing Times
Arthritis drug could also help combat ovarian cancer  Nursing Times
CAR T-cell therapy may be a ‘miracle,' but it is too soon to say ‘cure' - Healio
CAR T-cell therapy may be a ‘miracle,' but it is too soon to say ‘cure'  Healio
Blood test could provide an early arthritis warning - Nursing Times
Blood test could provide an early arthritis warning  Nursing Times
Treatment for finger-bending disease may be ‘gamechanger' - The Guardian
Treatment for finger-bending disease may be ‘gamechanger'  The Guardian
Treatments for rheumatoid arthritis: Traditional DMARDS vs. biologics - Medical News Today
Treatments for rheumatoid arthritis: Traditional DMARDS vs. biologics  Medical News Today
How does alcohol affect rheumatoid arthritis (RA)? - Medical News Today
How does alcohol affect rheumatoid arthritis (RA)?  Medical News Today
Triple Treatment Effective in Early Rheumatoid Arthritis - Medscape
Triple Treatment Effective in Early Rheumatoid Arthritis  Medscape
Benefits and side effects of LDN for rheumatoid arthritis - Medical News Today
Benefits and side effects of LDN for rheumatoid arthritis  Medical News Today
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis - The New England Journal of Medicine
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis  The New England Journal of Medicine
Chinese herbal remedy 'just as effective as methotrexate against arthritis' - Medical News Today
Chinese herbal remedy 'just as effective as methotrexate against arthritis'  Medical News Today
Ankylosing spondylitis: an update - Royal Australian College of General Practitioners (RACGP)
Ankylosing spondylitis: an update  Royal Australian College of General Practitioners (RACGP)
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis - The New England Journal of Medicine
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis  The New England Journal of Medicine

Articles/peer reviewed publications and
Lay Summaries

  • B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure.
    Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC- R4RA investigators. 
    Arthritis Rheumatol. 2019 Nov 29.
    https://doi.org/10.1002/art.41184
    See Lay Summary




The R4-RA trial is funded by the MRC-NIHR Efficacy and
Mechanism Evaluation Programme