Highlights and News

Leeds leads global trial of groundbreaking cell therapy for autoimmune diseases - National Health Executive
Leeds leads global trial of groundbreaking cell therapy for autoimmune diseases  National Health Executive
PEPITEM Regulates the Synovial Microenvironment During Immune-Mediated Inflammatory Arthritis to Limit Disease - Wiley & Sons
PEPITEM Regulates the Synovial Microenvironment During Immune-Mediated Inflammatory Arthritis to Limit Disease  Wiley & Sons
Review of the European Alliance of Associations for Rheumatology (EULAR) 2026 Congress - EMJ
Review of the European Alliance of Associations for Rheumatology (EULAR) 2026 Congress  EMJ
Why Rheumatoid Arthritis Remission Rates Remain Stagnant - EMJ
Why Rheumatoid Arthritis Remission Rates Remain Stagnant  EMJ
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients - Nature
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients  Nature
Championing physio for inflammatory arthritis - The Chartered Society of Physiotherapy
Championing physio for inflammatory arthritis  The Chartered Society of Physiotherapy
New gene study offers arthritis treatment insights - HealthandCare.scot
New gene study offers arthritis treatment insights  HealthandCare.scot
8 Diseases That Could Mimic Rheumatoid Arthritis - and Delay Your Diagnosis - CreakyJoints
8 Diseases That Could Mimic Rheumatoid Arthritis - and Delay Your Diagnosis  CreakyJoints
‘Milestone' as NICE recommends biologics in moderate rheumatoid arthritis for the first time - The Pharmaceutical Journal
‘Milestone' as NICE recommends biologics in moderate rheumatoid arthritis for the first time  The Pharmaceutical Journal
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis - NEJM
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis  NEJM
Tight Control of Psoriatic Arthritis: Real-World Outcomes From TICOPA - Rheumatology Advisor
Tight Control of Psoriatic Arthritis: Real-World Outcomes From TICOPA  Rheumatology Advisor
Crying out for equity: outcomes of rheumatic diseases confounded by ethnicity | Clinical Rheumatology - Springer Nature Link
Crying out for equity: outcomes of rheumatic diseases confounded by ethnicity | Clinical Rheumatology  Springer Nature Link
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis - Wiley Online Library
Nurse-led care for people with early rheumatoid arthritis: Interview study with thematic analysis  Wiley Online Library
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis - Nature
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis  Nature
Trial suggests JAK1 inhibitor is superior to methotrexate for treatment of early rheumatoid arthritis - The Pharmaceutical Journal
Trial suggests JAK1 inhibitor is superior to methotrexate for treatment of early rheumatoid arthritis  The Pharmaceutical Journal
Using Polygenic Risk Scores to Aid Diagnosis of Patients With Early Inflammatory Arthritis: Results From the Norfolk Arthritis Register - Wiley & Sons
Using Polygenic Risk Scores to Aid Diagnosis of Patients With Early Inflammatory Arthritis: Results From the Norfolk Arthritis Register  Wiley & Sons
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review - EMJ
Editor's Pick: JAK Inhibitors in the Treatment Algorithm of Rheumatoid Arthritis: A Review  EMJ
Identification, Monitoring, and Management of Rheumatoid Arthritis-Associated Interstitial Lung Disease - Wiley & Sons
Identification, Monitoring, and Management of Rheumatoid Arthritis-Associated Interstitial Lung Disease  Wiley & Sons
Is There a Missing Link in Rheumatoid Arthritis Management? - EMJ
Is There a Missing Link in Rheumatoid Arthritis Management?  EMJ
The Impact of Targeted Rheumatoid Arthritis Pharmacologic Treatment on Mental Health - Wiley & Sons
The Impact of Targeted Rheumatoid Arthritis Pharmacologic Treatment on Mental Health  Wiley & Sons
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA - HealthCentral
PsA Takes Longer to Diagnose and Gets Less Early Therapy Than RA  HealthCentral
Are There Natural Remedies for Rheumatoid Arthritis? - Cleveland Clinic Health Essentials
Are There Natural Remedies for Rheumatoid Arthritis?  Cleveland Clinic Health Essentials
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics | Scientific Reports - Nature
Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics | Scientific Reports  Nature
Asian and older rheumatoid arthritis sufferers 50% less likely to receive targeted treatment, finds study - Medical Xpress
Asian and older rheumatoid arthritis sufferers 50% less likely to receive targeted treatment, finds study  Medical Xpress
Blocking the immune system in rheumatoid arthritis - The Pharmaceutical Journal
Blocking the immune system in rheumatoid arthritis  The Pharmaceutical Journal
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis - NEJM
Sustained Remission with Etanercept Tapering in Early Rheumatoid Arthritis  NEJM
COPD: A Major Predictor of Early Mortality in Rheumatoid Arthritis - Rheumatology Advisor
COPD: A Major Predictor of Early Mortality in Rheumatoid Arthritis  Rheumatology Advisor
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure - The New England Journal of Medicine
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure  The New England Journal of Medicine
Lipidome profile predictive of disease evolution and activity in rheumatoid arthritis - Nature
Lipidome profile predictive of disease evolution and activity in rheumatoid arthritis  Nature
Rheumatoid arthritis - Nature
Rheumatoid arthritis  Nature
Rheumatoid arthritis diagnosis and management: a clinical update - Nursing Times
Rheumatoid arthritis diagnosis and management: a clinical update  Nursing Times
Psoriatic Arthritis in the Ankle: Could Your Ankle Pain Be a Sign of Psoriatic Arthritis? - CreakyJoints
Psoriatic Arthritis in the Ankle: Could Your Ankle Pain Be a Sign of Psoriatic Arthritis?  CreakyJoints
Addressing the rheumatic disease diagnostic gap via the lab - Laboratory News
Addressing the rheumatic disease diagnostic gap via the lab  Laboratory News
Meera Alagarajah on dealing with rheumatoid arthritis - Dentistry Online - Dentistry.co.uk
Meera Alagarajah on dealing with rheumatoid arthritis - Dentistry Online  Dentistry.co.uk
Arthritis drug shows potential in skin cancer - PharmaTimes
Arthritis drug shows potential in skin cancer  PharmaTimes
Hand Exercise in Rheumatoid Arthritis: A Clinician's Perspective - Rheumatology Advisor
Hand Exercise in Rheumatoid Arthritis: A Clinician's Perspective  Rheumatology Advisor
Integrating point-of-care ultrasound into rheumatology practice - Medycyna Praktyczna
Integrating point-of-care ultrasound into rheumatology practice  Medycyna Praktyczna
Quell launches chill phase 1/2 trial for novel cartreg therapy - PharmaTimes
Quell launches chill phase 1/2 trial for novel cartreg therapy  PharmaTimes
Migratory arthritis: Causes, prevention, and more - Medical News Today
Migratory arthritis: Causes, prevention, and more  Medical News Today
Rheumatoid arthritis begins years before symptoms, study finds - Medical News Today
Rheumatoid arthritis begins years before symptoms, study finds  Medical News Today
Ibuprofen for arthritis: Is it safe to take every day? - Medical News Today
Ibuprofen for arthritis: Is it safe to take every day?  Medical News Today
UK waiting times for RA and PsA patients: an interview with Dr Marwan Bukhari, Consultant Rheumatologist at the University Hospitals of Morecambe Bay NHS Foundation Trust - News-Medical
UK waiting times for RA and PsA patients: an interview with Dr Marwan Bukhari, Consultant Rheumatologist at the University Hospitals of Morecambe Bay NHS Foundation Trust  News-Medical
The breakthrough that could stop arthritis and diabetes in their tracks - The i Paper
The breakthrough that could stop arthritis and diabetes in their tracks  The i Paper
Clinical Review - Rheumatoid arthritis - GPonline
Clinical Review - Rheumatoid arthritis  GPonline
Rheumatoid Arthritis: Common Questions About Diagnosis and Management - American Academy Of Family Physicians | AAFP
Rheumatoid Arthritis: Common Questions About Diagnosis and Management  American Academy Of Family Physicians | AAFP
PEPITEM 'replacement therapy' shows potential for early-stage inflammatory arthritis - Medical Xpress
PEPITEM 'replacement therapy' shows potential for early-stage inflammatory arthritis  Medical Xpress
Minocycline for rheumatoid arthritis: What to know - Medical News Today
Minocycline for rheumatoid arthritis: What to know  Medical News Today
Turmeric for rheumatoid arthritis: Does it work? - Medical News Today
Turmeric for rheumatoid arthritis: Does it work?  Medical News Today
22 natural treatments for psoriatic arthritis - Medical News Today
22 natural treatments for psoriatic arthritis  Medical News Today
New drug Bimzelx shows promise as a treatment for psoriatic arthritis - Medical News Today
New drug Bimzelx shows promise as a treatment for psoriatic arthritis  Medical News Today
What to know about rheumatoid arthritis and intermittent fasting - Medical News Today
What to know about rheumatoid arthritis and intermittent fasting  Medical News Today
Treatments for rheumatoid arthritis: Traditional DMARDS vs. biologics - Medical News Today
Treatments for rheumatoid arthritis: Traditional DMARDS vs. biologics  Medical News Today
First Enbrel biosimilar launches in UK - Pharmafile
First Enbrel biosimilar launches in UK  Pharmafile
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis - NEJM
Infliximab and Methotrexate in the Treatment of Rheumatoid Arthritis  NEJM
Ankylosing spondylitis: an update - Royal Australian College of General Practitioners (RACGP)
Ankylosing spondylitis: an update  Royal Australian College of General Practitioners (RACGP)
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis - NEJM
The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis  NEJM
England | London | Six taken ill after drug trials - BBC
England | London | Six taken ill after drug trials  BBC
Blood test could provide an early arthritis warning - Nursing Times
Blood test could provide an early arthritis warning  Nursing Times

Articles/peer reviewed publications and
Lay Summaries

  • B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure.
    Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC- R4RA investigators. 
    Arthritis Rheumatol. 2019 Nov 29.
    https://doi.org/10.1002/art.41184
    See Lay Summary




The R4-RA trial is funded by the MRC-NIHR Efficacy and
Mechanism Evaluation Programme